Non-muscle myosin II-dependent cumulus cell migration at ovulation is required for sperm to reach the egg in mice

Non-muscle myosin II-dependent cumulus cell migration at ovulation is required for sperm to reach the egg in mice

We began by collecting COCs from large antral follicles of eCG-primed mice and incubating them in medium supplemented with EGF to induce expansion. After 4 h of incubation, no change in the volume of the COCs was apparent, as assessed by…

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