The ALEX trial (NCT02075840) represents one of the most pivotal studies in the evolution of treatment for anaplastic lymphoma kinase–positive (ALK+) non–small cell lung cancer (NSCLC). The trial’s earlier findings led to…
Category: 6. Business
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Dato-DXd Doubles Response Rates and Extends Survival in First-Line Metastatic TNBC
Q: Could you summarize the magnitude of benefit seen with Dato-DXd compared to chemotherapy in this first-line mTNBC population and comment on how clinically meaningful this is for practice?
Rebecca Dent, MD: As we know, patients with metastatic…Continue Reading
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PAM Inhibition Adds Value in HR+/HER2- PIK3CA Wild Type Advanced Breast Cancer
The addition of the PI3K/AKT/mTOR (PAM) inhibitor gedatolisib to fulvestrant (Faslodex), with or without palbociclib (Ibrance) led to clinically meaningful and statistically significant improvements in progression-free survival (PFS) among…
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DESTINY-Breast11: Neoadjuvant T-DXd/THP Improves pCR in High-Risk HER2+ BC | Targeted Oncology
Neoadjuvant fam-trastuzumab deruxtecan-nxki (T-DXd; Enhertu) followed by paclitaxel, trastuzumab (Herceptin), and pertuzumab (Perjeta; THP) yielded benefit in pathologic complete response (pCR) rates compared with dose-dense doxorubicin and…
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Like Jeff Bezos and Howard Schultz, Chess.com’s cofounder says people doubted his vision—with a 225 million-user empire, he’s now having the last laugh
In any entrepreneur’s journey, there are bound to be naysayers and doors slammed in their face.
When Jeff Bezos was drumming up his early visions of Amazon while working as a hedge fund manager, his Wall Street boss questioned if he could…
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Sam Altman wants to ‘treat adults like adults’—but can OpenAI keep ChatGPT safe after opening the door to erotica?
OpenAI chief executive Sam Altman has announced that ChatGPT will soon be able to generate erotica for verified adult users. The move, framed by Altman as an effort to “treat adult users like adults,” comes as the company faces scrutiny over…
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Carasso sells 1/3 of “Carasso Nia” apartments in Jerusalem
Carasso sells 1/3 of “Carasso Nia” apartments in Jerusalem | The Jerusalem PostJerusalem Post/Business & Innovation/Israel Real EstateAmid reports of a slowdown in Jerusalem’s housing market, Carasso has sold one-third of its luxury “Carasso Nia”…
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Does Cognizant’s New AI Coding Blueprint Expand the Long-Term Growth Story for CTSH?
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Cognizant Technology Solutions recently announced the launch of its Enterprise Vibe Coding Blueprint, a suite of services and reusable intellectual property that enables large enterprises to securely and efficiently operationalize AI-assisted…
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Negative Effects of the Trade War Offset by the AI Boom and the Industrial Renaissance
Contrary to widespread fears about the economic outlook, key credit indicators are turning more bullish. Default rates for high yield debt and loans have peaked, along…
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Meet AMIES, China’s new hope in breaking reliance on ASML’s chipmaking machines
AMIES Technology, a new Chinese lithography equipment manufacturer that showcased its latest chipmaking products at an industry event in Shenzhen last week, is offering renewed optimism in the nation’s drive to reduce its dependence on Dutch…
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